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Wednesday, June 7 • 10:00 - 10:45
Keynote Lecture - Compound Management and Hit Discovery for the 2020’s - Steve Rees

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Compound Management and Hit Discovery for the 2020’s

Steve Rees, Vice-President, Screening Sciences and Sample Management

Success in drug discovery requires the rapid identification of multiple tractable hit series for every target.  This requires innovation in the quality and composition of compound collections, innovative ways of accessing novel chemistry, the implementation of advanced screening automation and assay platforms, and the development of new ways of working between and across pharma and academia.  From 2018, AstraZeneca’s hit discovery capabilities will be located within the AZ Medical Research Council UK Centre for Lead Discovery at the AstraZeneca research campus in Cambridge.  The centre will support up to 50 academic and pharma hit discovery projects each year with scientists from AstraZeneca, the Medical Research Council and Cancer Research UK working side by side.  In this presentation I will describe the vision for the UK Centre for Lead Discovery, the technology innovations being implemented in Compound Management and High Throughput Screening to create new capability, and the strategies being adopted to enrich the quality and diversity of the compound library to meet the aspiration of multiple quality hit series for every drug target.


Speakers
avatar for Steve Rees

Steve Rees

VP, Screening Sciences and Sample Management, AstraZeneca
Steve Rees is Vice-President of Screening Sciences and Sample Management at AstraZeneca with global responsibility for Compound Management, the human tissue BioBank, Hit Discovery and Lead Optimisation biology support to preclinical discovery projects. | | Prior to joining AstraZeneca, Steve worked at GlaxoSmithKline for 24 years in various... Read More →


Wednesday June 7, 2017 10:00 - 10:45
Auditorium 4