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Wednesday, June 7 • 09:00 - 10:00
Plenary Lecture - PNA-programmed Self Assemblies in Chemical Biology - Nicolas Winssinger

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PNA-programmed Self Assemblies in Chemical Biology

The programmable nature of nucleic acid hybridization has inspired a number of applications beyond their natural function in heredity.  Peptide Nucleic Acids (PNA) are endowed with attractive properties for this endeavor as they are more robust and form more stable duplex than their natural counter parts. Several applications from our laboratory to program self-assemblies of small molecules, template chemical reactions or display multimeric ligands will be presented.

avatar for Nicolas Winssinger

Nicolas Winssinger

Professor, University of Geneva
Nicolas Winssinger is professor at the university of Geneva.  He began his independent career in 2002 at the Institut de Science et Ingénierie Supramoléculaires, Strasbourg.  He carried out his PhD under the guidance of K.C. Nicolaou (The Scripps Research Institute) and postdoctoral training with P.G. Schultz (NIH postdoctoral fellow). An important theme is the use of natural product synthesis to aid in the development of chemical biology probes, with a particular emphasis on natural product that inhibit their target through covalent interactions. Another important theme throughout his research is the use of unnatural nucleic acid (PNA) to encode molecules, program spatial organization of ligands and direct reactions. A long-term objective is to extend these principles towards complex systems which can emulate some of the fundamental features of living... Read More →

Wednesday June 7, 2017 09:00 - 10:00
Auditorium 4